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The following peer-reviewed papers directly related to Cimbi have been published in 2019.

  1. da Cunha-Bang S, Ettrup A, Mc Mahon B, Skibsted AP, Schain M, Lehel S, Dyssegaard A, Jørgensen LM, Møller K, Gillings N, Svarer C, Knudsen GM. Measuring endogenous changes in serotonergic neurotransmission with [11C]Cimbi-36 positron emission tomography in humans. Transl Psychiatry. 2019 Apr 11;9(1):134
  2. Erritzoe D, Smith J, Fisher PM, Carhart-Harris R, Frokjaer VG, Knudsen GM. Recreational use of psychedelics is associated with elevated personality trait openness: Exploration of associations with brain serotonin markers. J Psychopharmacol. 2019 Sep;33(9):1068-1075
  3. Griem-Krey N, Klein AB, Herth M, Wellendorph P. Autoradiography as a Simple and Powerful Method for Visualization and Characterization of Pharmacological Targets. J Vis Exp. 2019 Mar 12;(145)
  4. Hansen HD, Constantinescu CC, Barret O, Herth MM, Magnussen JH, Lehel S, Dyssegaard A, Colomb J, Billard T, Zimmer L, Tamagnan G, Knudsen GM. Evaluation of [18 F]2FP3 in pigs and non-human primates. J Labelled Comp Radiopharm. 2019 Jan;62(1):34-42
  5. Hjordt LV, Stenbæk DS. Sensory processing sensitivity and its association with seasonal affective disorder. Psychiatry Research. 2019 Feb;272:359-364
  6. Jensen CG, Krogh SC, Westphael G, Hjordt LV. Mindfulness is positively related to socioeconomic job status and income and independently predicts mental distress in a long-term perspective: Danish validation studies of the Five-Factor Mindfulness Questionnaire. Psychol Assess. 2019 Jan;31(1):e1-e20
  7. Johansen A, Holm S, Dall B, Keller S, Kristensen JL, Knudsen GM, Hansen HD. Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions. EJNMMI Res. 2019 Jul 31;9(1):71
  8. Lansner J, Jensen CG, Petersen A, Fisher PM, Frokjaer VG, Vangkilde S, Knudsen GM. Three weeks of SSRI administration enhances the visual perceptual threshold - a randomized placebo-controlled study. Psychopharmacology (Berl). 2019 Jun;236(6):1759-1769
  9. Larsen LK, Frøkjaer VG, Nielsen JS, Skrobik Y, Winkler Y, Møller K, Petersen M, Egerod I. Delirium assessment in neuro-critically ill patients: A validation study. Acta Anaesthesiol Scand. 2019 Mar;63(3):352-359
  10. L'Estrade ET, Hansen HD, Falk-Petersen C, Haugaard A, Griem-Krey N, Jung S, Lüddens H, Schirmeister T, Erlandsson M, Ohlsson T, Knudsen GM, Herth MM, Wellendorph P, Frølund B. Synthesis and Pharmacological Evaluation of [11C]4-Methoxy-N-[2-(thiophen-2-yl)imidazo[1,2-a]pyridin-3-yl]benzamide as a Brain Penetrant PET Ligand Selective for the δ-Subunit-Containing γ-Aminobutyric Acid Type A Receptors. ACS Omega. 2019 May 22;4(5):8846-8851
  11. Magnusson PO, Boer VO, Marsman A, Paulson OB, Hanson LG, Petersen ET. Gamma-aminobutyric acid edited echo-planar spectroscopic imaging (EPSI) with MEGA-sLASER at 7T. Magn Reson Med. 2019 Feb;81(2):773-780
  12. Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG. Genome-wide gene expression in a pharmacological hormonal transition model and its relation to depressive symptoms. Acta Psychiatr Scand. 2019 Jul;140(1):77-84
  13. Mehta D, Rex-Haffner M, Søndergaard HB, Pinborg A, Binder EB, Frokjaer VG. Evidence for oestrogen sensitivity in perinatal depression: pharmacological sex hormone manipulation study. Br J Psychiatry. 2019 Sep;215(3):519-527
  14. Ozenne B, Tae-Hee C, Mikkelsen IK, Hermier M, Thomalla G, Pedraza S, Roy P, Berthezène Y, Nighoghossian N, Østergaard L, Baron JC, Maucort-Boulch D. Individualized Quantification of the Benefit from Reperfusion Therapy using Stroke Predictive Models. Eur J Neurosci. 2019 Oct;50(8):3251-3260
  15. Prabhakaran J, DeLorenzo C, Zanderigo F, Knudsen GM, Gilling N, Pratap M, Jorgensen MJ, Daunais J, Kaplan JR, Parsey RV, Mann JJ, Kumar D. In vivo PET Imaging of [11C]CIMBI-5, a 5-HT2AR Agonist Radiotracer in Nonhuman Primates. J Pharm Pharm Sci. 2019;22(1):352-364
  16. Stenbæk DS, Budtz-Jørgensen E, Pinborg A, Jensen PS, Frokjaer VG. Neuroticism modulates mood responses to pharmacological sex hormone manipulation in healthy women. Psychoneuroendocrinology. 2019 Jan;99:251-256
  17. Stenbaek DS, Kristiansen S, Burmester D, Madsen MK, Frokjaer VG, Knudsen GM, Fisher PM. Trait Openness and serotonin 2A receptors in healthy volunteers: A positron emission tomography study. Hum Brain Mapp. 2019 May;40(7):2117-2124
  18. Sundström Poromaa I, Comasco E, Bäckström T, Bixo M, Jensen P, Frokjaer VG. Negative Association Between Allopregnanolone and Cerebral Serotonin Transporter Binding in Healthy Women of Fertile Age. Front Psychol. 2019 Jan 11;9:2767
  19. Vassilieva A, Olsen MH, Peinkhofer C, Knudsen GM, Kondziella D. Automated pupillometry to detect command following in neurological patients: a proof-of-concept study. PeerJ. 2019 May 13;7:e6929