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The following peer-reviewed papers directly related to Cimbi have been published in 2010.


  1. Abrahamsen TJ, Hansen LK. Regularized Pre-image Estimation for Kernel PCA De-noising Input Space Regularization and Sparse Reconstruction. Journal of Signal Processing Systems 2010(61), Springer New York.
  2. Aznar S, Klein AB, Santini MA, Knudsen GM, Henn F, Gass P, Vollmayr B. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse 2010a; 64(7):561-565.
  3. Baare WF, Vinberg M, Knudsen GM, Paulson OB, Langkilde AR, Jernigan TL, Kessing LV. Hippocampal volume changes in healthy subjects at risk of unipolar depression. J Psychiatr Res. 2010;44(10):655-662.
  4. Benveniste H, Fowler JS, Rooney WD, Scharf BA, Backus WW, Izrailtyan I, Knudsen GM, Hasselbalch SG, Volkow ND. Cocaine is pharmacologically active in the nonhuman primate fetal brain. Proc Natl Acad Sci U S A 2010; 107(4):1582-1587.
  5. Ebdrup BH, Glenthoj B, Rasmussen H, Aggernaes B, Langkilde AR, Paulson OB, Lublin H, Skimminge A, Baare W. Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia. J Psychiatry Neurosci 2010; 35(2):95-104.
  6. Erritzoe D., Holst K., Frokjaer V.G., Licht C.L., Kalbitzer J.  Nielsen F.Aa., Svarer C., Madsen J., Knudsen G.M. A non-linear relationship between cerebral serotonin transporter and 5-HT2A receptor binding: An in vivo molecular imaging study in humans. J Neurosci. 2010 Mar 3;30(9):3391-7.
  7. Erritzøe D, Frøkjær VG, Haahr MT, Kalbitzer J, Svarer C, Holst KK, Hansen DL, Jernigan T, Lehel S. Cerebral serotonin transporter binding is inversely related to body mass index. Neuroimage 2010b;1;52(1):284-9.
  8. Ettrup A, Palner M, Gillings N, Santini MA, Hansen M, Kornum BR, Rasmussen LK, Någren K, Madsen J, Begtrup M, Knudsen GM. Radiosynthesis and evaluation of [11C]Cimbi-5 as a 5-HT2A receptor agonist radioligand for PET. J Nucl Med 2010a;51(11):1763-70.
  9. Frokjaer VG, Vinberg M, Erritzoe D, Baare W, Holst KK, Mortensen EL, Arfan H, Madsen J, Jernigan TL, Kessing LV, Knudsen GM. Familial Risk for Mood Disorder and the Personality Risk Factor, Neuroticism, Interact in Their Association with Frontolimbic Serotonin 2A Receptor Binding. Neuropsychopharmacology. 2010a; 35(5):1129-1137.
  10. Frokjaer VG, Erritzøe D, Juul A, Nielsen FA, Holst K, Svarer C, Madsen J, Paulson OB, Knudsen GM. Endogenous plasma estradiol in healthy men is positively correlated with cerebral cortical serotonin 2A receptor binding. Psychoneuroendocrinology. 2010b;35(9):1311-20.
  11. Holm P, Ettrup A, Klein AB, Santini MA, El-Sayed M, Elvang AB, Stensbøl TB, Mikkelsen JD,  Knudsen GM, Aznar S. Plaque deposition dependent decrease in 5-HT_2A serotonin receptor in APP**swe/PS1dE9 amyloid overexpressing mice. J Alzheimers Dis 2010;1;20(4):1201-13.
  12. Kalbitzer J, Erritzøe D, Holst KK, Nielsen FA, Marner L, Lehel S, Arentzen T, Jernigan TL, Knudsen GM. Seasonal changes in brain serotonin transporter binding in short 5-HTTLPR-allele carriers but not in long-allele homozygotes. Biol Psych 2010;67(11):1033-9.
  13. Klein AB, Trajkovska V, Erritzøe D, Haugbøl S, Madsen J, Baaré W, Aznar S, Knudsen GM. Cerebral 5-HT2A receptor and serotonin transporter binding in humans are not affected by the val66met BDNF polymorphism status or blood BDNF levels. J Cereb Blood Flow Metab 2010b;30(11):e1-7.
  14. Klein AB, Santini M, Aznar S, Knudsen GM, Rios M. Changes in 5-HT(2A)-mediated behavior and 5-HT(2A)- and 5-HT(1A) receptor binding and expression in conditional brain-derived neurotrophic factor knock-out mice. Neuroscience 2010c;169(3):1007-1016.
  15. Koefoed P, Woldby DPD, Hansen TO, Hansen ES, Knudsen GM, Bolwig TG, Rehfeld JF. Gene variations in the cholecystokinin system in patients with panic disorder. Psychiatr Genet 2010;20(2):59-64.
  16. Kornum BR, Stott SRW, Mattsson B, Wisman L, Ettrup A, Hermening A, Knudsen GM and Kirik D. Adeno-associated viral vector serotypes 1 and 5 targeted to the neonatal rat and pig striatum induce widespread transgene expression in the forebrain. Experimental Neurology 2010; 222(1):70-85.
  17. Koziorowski J, Larsen P, Gillings N. A quartz-lined carbon-11 target: striving for increased yield and specific activity. Nucl Med Biol. 2010;37(8):943-8.
  18. Kramer V, Herth MM, Santini MA, Palner M, Knudsen GM, Rösch F. Structural combination of established 5-HT2A receptor ligands: New aspects of binding mode. Chem Biol Drug Des. 2010;76(4):361-6.
  19. Licht CL, Kirkegaard L, Zueger M, Chourbaji S, Gass P, Aznar S, Knudsen GM. Changes in 5-HT(4) receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice. Neurochem Int 2010; 56(4):603-610.
  20. Licht CL, Knudsen GM, Sharp T. Effects of the 5-HT4 receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience Letters. 2010b;476(2):58-61.
  21. Madsen KS, Baare WF, Vestergaard M, Skimminge A, Ejersbo LR, Ramsoy TZ, Gerlach C, Akeson P, Paulson OB, Jernigan TL. Response inhibition is associated with white matter microstructure in children. Neuropsychologia. 2010; 48(4):854-862.
  22. Marner L, Gillings N, Madsen K, Erritzoe D, Baare WF, Svarer C, Hasselbalch SG, Knudsen GM. Brain Imaging of Serotonin 4 Receptors in Humans with [(11)C]SB207145-PET. Neuroimage. 2010; 50(3):855-861.
  23. Mikkelsen JD, Thomsen MS, Hansen H, Lichota J. Use of biomarkers in discovery of novel anti-schizophrenia drugs. Drug Discov Today 2010; 15(3-4):137-141.
  24. Mørup M, Madsen KH, Dogonowski AM, Siebner H, Hansen LK. Infinite Relational Modeling of Functional Connectivity in Resting State fMRI. Proc. Neural Information Processing Systems 2010, 2010.
  25. Nielsen FÅ. A fielded wiki for personality genetics. Proceedings of the 6th International Symposium on Wikis and Open Collaboration WikiSym’10. Gdansk, Poland. ACM New York, NY, USA 2010; 16:1-2
  26. Palner M, McCormick P, Gillings N, Rasmussen LK, Begtrup MWAA, Knudsen GM. Radiosynthesis and ex vivo evaluation of (R)-(-)-2-chloro-N-[1-11C-propyl]n-propylnorapomorphine. Nucl Med Biology 2010; 37(1):35-40.
  27. Palner M, McCormick P, Parkes J, Knudsen GM, Wilson AA. Systemic catechol-O-methyl transferase inhibition enables the D1 agonist radiotracer R-[11C]SKF 82957. Nucl Med Biol 2010b;37(7):837-43.
  28. Paulson OB, Hasselbalch SG, Rostrup E, Knudsen GM, Pelligrino D. Cerebral blood flow response to functional activation. J Cereb Blood Flow Metab 2010; 30(1):2-14.
  29. Paterson LM, Tyacke RJ, Nutt DJ, Knudsen GM. Measuring endogenous 5-HT release by emission tomography: promises and pitfalls. J Cereb Blood Flow Metab 2010;30(10):1682-706.
  30. Prabhakaran J, Majo JM, Milak MS, Kassir SA, Palner M, Savenkova L, Mali P, Arango V, Mann JJ, Parsey RV. Synthesis, in vitro and in vivo evaluation of [11C]MMTP: A potential PET ligand for mGluR1 receptors. Bioorg Med Chem Lett 2010;20(12):3499-501.
  31. Rasmussen H, Erritzoe D, Andersen R, Ebdrup BH, Aggernaes B, Oranje B, Kalbitzer J, Madsen J, Pinborg LH, Baare W, Svarer C, Lublin H, Knudsen GM, Glenthoj B. Decreased frontal serotonin2A receptor binding in antipsychotic-naive patients with first-episode schizophrenia. Arch Gen Psychiatry 2010; 67(1):9-16.
  32. Stahlhut C, Attias HT, Wipf D, Hansen LK, Nagarajan SS. Sparse spatio-temporal inference of electromagnetic brain sources. Proc. Machine Learning in Medical Imaging (MLMI), Lecture Notes in Computer Science. (LNCS) 2010b;6357:157-164.
  33. Vinberg M, Froekjaer VG, Kessing LV. Coping styles in healthy individuals at risk of affective disorder. J Nerv Ment Dis 2010; 198(1):39-44.
  34. Wellendorph P, Høg S, Sabbatini P, Pedersen MH, Martiny L, Knudsen GM, Frølund B, Clausen RP, Bräuner-Osborne H. Novel radioiodinated {gamma}-hydroxybutyric acid analogues for radiolabeling and Photolinking of high-affinity {gamma}-hydroxybutyric acid binding sites. J Pharmacol Exp Ther. 2010;335(2):458-64.
  35. Wilkowski B, Szewczyk M, Rasmussen PM, Hansen LK, Nielsen FA. BredeQuery: Coordinate-Based Metaanalytic Search of Neuroscientific Literature from the SPM Environment.  Proc. Biomedical Engineering Systems and Technologies Communications in Computer and Information Science. 2010;52(4):314-324.
  36. Yourganov G, Schmah T, Small SL, Rasmussen PM, Strother SC. Functional connectivity metrics during stroke recovery. Arch Ital Biol. 2010;148(3):259-70.
  37. Ziebell M, Pinborg LH, Thomsen G, de Nijs R, Svarer C, Wagner A, Knudsen GM. MRI-guided region-of-interest delineation is comparable to manual delineation in dopamine transporter SPECT quantification in patients: a reproducibility study. J Nucl Med Technol 2010;38(2):61-8.
  38. Ziebell M, Holm-Hansen S, Thomsen G, Jensen P, Wagner A, Knudsen GM. Serotonin transporters in dopamine transporter imaging: A head-to-head comparison of dopamine transporter SPECT radioligands [123I]FP-CIT and [123I]PE2I. J Nucl Med 2010;51(12):1885-91.